Jay (0s):
Because number one, we wanna attack the biggest issue that you have for most Americans and really Western people, or first world people that are watching this podcast. It's fat loss, right? It's insulin resistance, it's too much inflammation, which is all those things. Again, insulin resistance and, and, and too much body fat. So we're probably gonna use like a GH agonist peptide, and we're probably gonna use a GLP peptide, and we're gonna use these things again in the context of health and longevity. So in micro dosages, you know, we're gonna use them a couple times a week to, depending on how much body fat you have to lose, and maybe three times a week. And we're gonna cycle these, right? We're gonna use these for six to eight to 10 weeks, and then we're gonna go off, and then we're gonna assess our experience, assess our results, and then we're gonna decide what's next.
Jay (44s):
Right?
Brian (45s):
This week I interviewed Jay Campbell. Jay is a five-time international bestselling author, men's physique champion, and the owner and co-founder of Bio Longevity Labs, Widely recognized as a leading expert on hormonal optimization, therapeutic peptides, and biohacking. Jay helps individuals break free from the failing secure system and take control of their health. We discussed the right and wrong way to use peptides along with What is GLP one, two, and three. How can someone start using peptides to optimize their health? What's s the fastest and healthiest way to lose those extra 10 to 15 pounds? And his one tip to get your body back to what it once was. Really enjoyed my interview with Jay.
Brian (1m 26s):
I know you will too. Thanks so much for listening and enjoy the show. All right, Welcome to the Get Lean, Eat Clean podcast. My name is Brian Gryn, and I have Jay Campbell on Welcome to the show.
Jay (1m 36s):
Brian, what's going on, brother? Thank you so much for having me. I'm very excited and humbled and privileged and honored to be on your podcast. So I know this is gonna be an epic show.
Brian (1m 45s):
It will be. I love the glasses little,
Jay (1m 49s):
These are raw optics. I got a bunch of companies that send me stuff, but I put the raw optics on. I also have these guys, which I forget their, I don't even know their name. It's dw, it stands for something, water makers or something. But I love wearing blue light blockers because as you know, EMF is very harmful to our eyes and also to our brains. That's a whole nother podcast.
Brian (2m 10s):
Yeah, maybe we'll touch on that. But I appreciate you coming on, and you know, you, you've been what, 20 years of hormone optimization? Correct. What, what sort of led you down that path?
Jay (2m 24s):
So really a very high level summary of my backstory. At 29, it was kicked in the testicles, playing in an adult men's basketball league. I checked out at the game, you know, keeled over, of course, and about eight weeks later, I started feeling extremely run down. And at the time I was 29, I was literally a couple months away from turning 30. I went to my PPO doctor. I lived in Southern California in Pasadena, and I worked for the Los Angeles Times as an advertising rep. And he referred me to a endocrinologist. And the guy actually happened to be like a world renowned Harvard educated endocrinologist named Raymond Scruggs, Dr. Raymond Scruggs. And he took my labs and he saw that I had the testosterone level of what he said, like as an 85-year-old plus geriatric. And he said he could put me on therapeutic testosterone and then have me write his reign in, you know, 6, 8, 10 weeks.
Jay (3m 9s):
And so I said, he said, go home, talk to your fiance at the time about doing this. And you know, once she says, yeah, you're okay, and then we'll do it. And so I did. And of course she said, yes, we didn't have kids at the time, and you gotta remember, this is in 1999. So there really wasn't a lot of people using therapeutic hormones. There was no internet talking about it. There was nothing like we have today. But anyway, I went on, did what he said, and eight weeks later I felt absolutely amazing. I was all my low back pain. And, you know, just the, the feelings of low testosterone or testosterone deficiency went away. And when I went to see him, you know, for my, you know, checkup, he was like, okay, we can take you off. And I'm like, bro, I'm not coming off this, this is the most transformative, life altering thing I've ever experienced.
Jay (3m 51s):
And so at that point, I worked with him for a couple more years, and then he moved, I, I forgot, I think he moved to Northern California or something. So I ended up getting a different doctor. But anyway, over that next 14 to 15 years, I experimented with therapeutic hormones. I also started using therapeutic peptides. You know, I started using peptides in 2003, right? So back then for people using therapeutic hormones or peptides or whatever, there wasn't an internet. There wasn't, you know, Reddit, there weren't places to learn. You really just had to be an underground anonymous forums like performance enhancement, bodybuilding, et cetera. And you were sharing it really cloud sourcing your information as like, kind of like a Guinea pig or, or, or, you know, just a general user with other people who are really smart and also doing the same thing.
Jay (4m 38s):
Whereas, as you know, now today, unfortunately, the internet, the signal to noise ratio is almost all noise and very little signal. It's very hard for people to get really good information. There's so many people online talking about peptides and hormones who absolutely have no earthly idea what they're talking about. But then there was really good information. So, you know, I, I obviously, I built a really awesome physique over that time. I still was in the advertising world, worked in the digital automotive media world, and everyone who met me would always be they, they would ask me, they're like, wow, you have a very impressive physique. What do you do? And I would tell them, I use therapeutic testosterone, and I would always be met with like, Ooh, steroids or, wow, fascinating. Tell me more. And eventually the fascinating, tell me more, crowd won out.
Jay (5m 21s):
And they said, you need to write a book about this. You know more about this than almost any doctor, which is sadly, unfortunately still true today. And so I eventually wrote a book which came out, it was actually written in 2014, but published in 2015. It was called the Definitive TRT Manual. It exploded on Amazon. It was like number one group, number one book in Men's Health for like four or five months in, in 2016. In fact, a lot of people think that Jeff Bezos read it And, you know, went from the pipsqueak guy to the dude wearing, you know, open shirt, chest, you know, walking on yachts, because obviously I did a really good job of explaining it to lay people and like how to use it, where to find doctors, et cetera. And then to make a very long story short, you know, since then I've written eight books.
Jay (6m 4s):
My newest book was just published 10 days ago, or 11 days ago now, called Metabolic Awakening with GLP one Peptides. And it's exploding actually into mainstream consciousness. In fact, the Manhattan Book Club just reached out to me today and said they want me to come up and lecture on a series on GLP. So, you know, like I said, to make a very long story short, I've written about 10 books. I lecture now all across the world about therapeutic peptides, about therapeutic testosterone. My Peptides book came out in 2023, really at the peak of mainstream awareness becoming about, And you know, I didn't design it that way. It just kinda randomly came out in February 1st, 2023. And that book also blew up. And you know, obviously subsequently now I'm talking on podcasts with people like yourself and traveling all over the world, also promoting my, my brand or my, my company, which is called Bio Longevity Lapse.
Brian (6m 53s):
All right, thank you for that, that quick synopsis. Well, let's get into peptides. I mean, you got GLP 1, 2, 3, right? Yep. Yeah. And to help with, you know, metabolism, fat loss, repair, and aging. Yep. So why don't we dive into those and talks about what works, what doesn't and and how most people are probably using 'em wrong.
Jay (7m 17s):
Exactly. I'm glad you said that. 95% of people who are first exposed to GLP ones, and we, and I do want to break it down for people, absolutely do them wrong. And there's, there's really two reasons for that. And I, I really, it's hard for me to blame anyone because the truth is, Brian, you know this 'cause you the questions you just asked me. The pharmaceutical manufacturers of GLP have some of the brightest chemists and smartest people in the world that they employ. And you know, they created these products literally back in 20 2006. So two years after I started using therapeutic peptides, they were already, you know, in the weeds building these amazing drugs. Now, back then, they were very crude and they were created for people who had obesity and type two diabetes.
Jay (8m 2s):
And really it was mostly type two diabetes and insulin resistance. And eventually it became for people that were obese, because obviously they tie together, they're almost one and the same thing. But, you know, fast forward to 2019 and the first real GLP that people are familiar with, which is semaglutide, which people in the commercial market know as Wegovy, and I forget the other one. There's another one. But that drug was a stage one GLP. And what that means is a stage one GLP is literally appetite suppressing. And by the way, GLP one stands for glycogen like peptide. And basically glycogen is a cor is a hormone that's secreted in our body. It's, it's technically a fight or flight hormone. But by, by regulating or increasing or modulating kogen, you can stimulate metabolic rate, you can stimulate appetite suppression.
Jay (8m 49s):
And so by doing this stuff, the first phase, again, What GLP ones, all it really did was suppress appetite. And so you have sema, which again is known as wegovy in the commercial marketplace. But that, and that's a GLP one go. Three years later, not even three years later, about two years later, GLP two came into the market. So we're looking now at like 2021, end of 2021. It was really around October of 2021. And it was called tirzepatide, which is sold in the marketplace by Eli Lilly under the two major trade names, Zep Mound and Manjaro. And it's, and a GLP two is obviously GLP one, appetite suppression, GLP two glucco in stimulating. So when you stimulate glucco and you also increase metabolic rate, so a GLP two is obviously more effective than a GLP one, right?
Jay (9m 35s):
Because the GLP one is just suppressing appetite. And then you add in the layer of also enhancing metabolic rate in GLP two. And so you have a much more effective product in the marketplace today. Those products are still both available. GLP one is sold by Novo Nordisk in the news in the last two days. They just made a big deal with that big global telehealth platform, him and hers, you know, to sell them exclusively. And then Eli Lilly, which is the most, the, the highest net worth company in the world, they just passed Apple. They're a trillion dollar company. They sell the GLP two. And by the way, you mentioned GLP three, which is called Rut ide. That's not FDA approved yet, But it will be F FDA A approved this year.
Jay (10m 18s):
You know, and I've been very outspoken about that drug because I've been using it as a research chemical since 2023 when it first came out. That will be the most powerful and the highest grossing drug in the history of pharmaceutical science right now. Tirzepatide is that has that title to that claim. And that was as of 2025. But Eli Lilly will have this drug, which is again, a GLP three. And by the way, a GLP three is appetite suppression, glucagon stimulating, and then nutrient partitioning and insulin signaling improving. So it's like three phases of, you know, metabolic improvement. And so it's easily the most effective. And anyone who's used it knows that it is more effective than the other two.
Jay (11m 0s):
I think, you know, you can ask me more questions about this as we go deeper, but I think people need to understand that there's a wrong way and a right way to use DLPs. And the pharmaceutical manufacturers want you to use them their way, which in my opinion is the wrong way. And their way means they start at a very high dose and then they titrate the dosage way higher over time. And what this does is, is a lot of things, but most importantly, it wax out people's receptors and it also causes lots of side effects. And so most people, when I told you 95% of people do these wrong, started with those very high pharmaceutical recommended dosages and then went higher and higher and higher over time.
Jay (11m 40s):
And then also did not do number two, which is change their lifestyle. So you have this gigantic industry, again, 95% of people who were first exposed to GMPs, who basically looked at them as magic bullets or easy buttons, and they didn't change your lifestyle and they didn't use a, what I call a microdose or a surgically precise dose that doesn't whack out the receptors. And so all those people experience the side effects that you've seen in the news, right? That everybody talks about face collapse, but collapse back collapse, muscle
Brian (12m 12s):
Collapse. Yeah. They, they turn into like a raisin.
Jay (12m 14s):
Yeah, they look exactly. They look like exactly, they look like a cancer survivor, a wasting patient or something like that. But all of these people have done everything wrong in the book that I just wrote that just came out again, you know, 11 days ago. I teach people how to do it right. But I also go through all of those side effects that people have experienced, and I completely elucidate each one. Why is this happening and how to avoid it. So the book kind of starts with a history of glp then my history using them both with myself, my wife, and then my clients and, and people that follow me online. And then I go into the side effects. And then I go into, okay, this is how we actually do this, right?
Jay (12m 56s):
And by the way, it has 1,280 scientific references. So I hammer all of the peer review and the, and the publicly available research, which is by the way, in it's, it's so numerous. It's incredible. And all of the research, by the way, conclusively proves, which they, the pharmaceutical companies love to suppress this. That if you do start with a slower, a lower dose, which again, as I call a microdose or a surgically precise, you know, a clinically longevity type dose, that the weight that is come off is usually permanent. You actually maintain the weight loss versus starting at the super high dose causing all the side effects and then creating, you know, metabolic hell if you wanna call it that after the fact. And then that's when all the people complained.
Jay (13m 36s):
There's also, as you know, millions of class action lawsuits against Novo, against Eli Lilly for a lot of these side effects. But they will all be eventually thrown out because again, they're caused by inaccurate dosing. And obviously, as you know, the pharmaceutical companies always have themselves indemnified against these things. So most of those lawsuits are gonna be thrown out. And again, I say this in the book and I'm very, very clear about how, how this is almost all of the side effects are avoidable if you live a lifestyle conducive to using these things in therapeutic surgically precise dosages. And again, I show all the evidence, I show all the science what does it can prove. And then anecdotally at the end of the book, I have a chapter called The Transformations.
Jay (14m 19s):
And it's basically 16 men and women from all over the world, all walks of life, you know, all ethnicities and economic backgrounds. And in their words, it talks about using these correctly, what it's done for their life. And of course there's a before and after picture. So it's a really, really deep dive book. And like I said, it's really exploding on Amazon right now. There's a lot of people that are reading it, it's over 700 pages. So it's very in depth and it's very technical in places, but it's also explained in very lay way so that the average person who's not a clinical, you know, professional can understand it.
Brian (14m 52s):
Yeah, no, makes a lot of sense. I mean, I don't have a lot of experience with it, but I mean I know some people that have used it. And is this something you think once you start and you're on it, is it something that, you know, you mentioned the lifestyle aspect, which I think obviously is a big piece of the puzzle. Exactly. Is it something that you have to use the rest of your life or is this something that maybe can help you sort of jumpstart?
Jay (15m 15s):
So that's a great question, Brian. So the answer is yes, maybe and no, And what I mean by that is, and I, you know, I've explained this 'cause it is a great question, and I've explained this on a couple other podcasts I've done recently. It's a tool in the tool belt. And that once you master using it correctly, you have it there whenever you want. So to answer your question more specifically, you know, if you're a morbidly obese person, you're probably gonna have to use this tool for a couple of years, right? You're gonna have to use it correctly. And, and this is obviously to get your weight into a healthy level, drop your insulin resistant, reduce your inflammation, et cetera. But if you're just a housewife, you know, or a guy in their forties or fifties or sixties who struggles with that, you know, 10 to 15 pounds of weight that they just can't seem to get rid of due to stubborn body fat, you know, genetic factors, poor, poor hormones, et cetera, it's the greatest tool ever because it literally changes brain programming in a positive way.
Jay (16m 15s):
And again, all the studies that have come out in the last year demonstrate that it cures obsessive compulsive disorders. So it literally, so I talk about this a lot in the book, and I've also talked a lot about this in podcasts. Most people in America who are not morbidly obese, who have, again, that say 10 to 15 to 20 pounds of fat to lose that they're always battling. The reason that they have this fat loss is for two, it's two, it's primary, two reasons. Number one, they have a hormonal deficiency, which goes undiagnosed because again, the medical establishment doesn't look into hormones. They look into again, you know, call it pharmaceutical interventions like SSRIs, right? You know, or you know, erectile dysfunction drugs, if they have sexual dysfunction, which so many people that suffer from hormone deficiencies do.
Jay (16m 59s):
But when you really look at this, it's really just because they're addicted to the chemicals in the American food supply. And by the way, it's a global food supply at this point. So if you can rewire people's brains, just, just mildly to ki to kill that addiction, that chemical addiction, and really again, it's called the hyper palliative addiction to food. And again, all these companies, the big agri companies spend millions actually hundreds of millions every year, you know, in the science to create these addictive chemicals that make people come back and eat, right? Like McDonald's, fries, Chick-fil-A sandwiches, et cetera. So if you can overcome that addiction, you can actually get a lot of these people to lose that last 10 to 15 to 20 pounds. And so that's what these chemicals do or, or these GLP do, especially GLP two and GLP three.
Jay (17m 42s):
And just so I say this to you, 'cause there's a chapter in the book on this, you know, I had to say this in the very beginning, in the introduction. I mean the, the drugs that I talk about in the book, which are so amazing now, like ide like tirzepatide Brian in two years, they may be irrelevant. That's how amazing this biochemical revolution that we're in right now. And it's how many amazing GLP fours and GLP fives and even GLP six are actually in the pipeline and we will be probably FDA approved within the next two to three years. So it's just, we're in a biochemical or biomedical golden age. There's so many amazing things coming into the marketplace. You know, one of the goals that I had with writing this book was to eliminate obesity. My mom who died in 2023 of a COVID diagnosis, I mean, very truthfully, dude, she was morbidly obese the last 20 years of her life.
Jay (18m 31s):
And you know, I have a personalized goal now of like stamping out obesity and we have the way to do it. These drugs can do it, but the problem is, is education. And number two, making them accessible. And obviously pharma is not educating their doctors, they're not educating the public. And again, they don't want to, they want people to take high dosages, whack out the receptors, get addicted to them, continue the cycle So they make more and more money. And then obviously it's the same thing with the docs. If, if we educate the docs or they educate the docs, they won't make as much money. And look, it's a vicious cycle because the docs make more money by prescribing more and higher doses. So, so it's very difficult to get the doctors to do it right, because then they make less money.
Jay (19m 14s):
But thankfully, there are enough doctors out there, there are enough educators like myself, subject matter experts that are teaching people how to do this right? And the proof is in the pudding when people do it right, they have transformational changes in their life.
Brian (19m 26s):
And would you say the biggest advantage to the GLP is the appetite suppressant?
Jay (19m 33s):
No, I would actually say the biggest advantage is the brain rewiring and the metabolic stimulation. Because again, remember thankfully we're not in a place yet where everybody's obese. We're actually on that path. If you look at the data in two thou, well this is actually already just insane, but right now, and this is from 2024 statistic, and this is in the book, 40% of men and women, I'm sorry, I just said that completely incorrectly, 70% of men and women in the United States over the age of 45 are considered obese by the BMI measurement. Now that is not a very good measurement of obesity because obviously muscular people are always categorized as obese.
Jay (20m 17s):
But my guess is that we got more than 50% of adults in America right now over the age of 45 are considered obese. And so if you extrapolate that data and you push to what they're predicting in 2035, or even before that, I think it's between 2032 and 2035, obesity will be the number one killer of humans in the planet. So if we can reduce that, and we can obviously do this through these drugs, through using them correctly, obviously changing your lifestyle. But here's the key about changing your lifestyle. The drugs make it really easy to do that because when they rewire the brain, they literally teach people, oh, I don't need to eat that hoho, or I don't need to eat those four McDonald's Big Macs, or whatever shit that I'm eating every single day because I'm addicted chemically to these ingredients.
Jay (21m 6s):
And so it really is kind of like an all causal, corrective mechanism because once you start taking these things in micro dosages, it instantly makes you wanna change your lifestyle. Like I've had thousands of people say to me, you know, in person and online through emails And you know, online correspondence over the last four years that once they started taking it correctly and judiciously again, microdosing, all their desire to eat shitty food went away. And a lot of people also become like, I don't wanna call it addicted, but energized towards activity and exercise. Whereas previously they never had the mindset to do it because they were in a malaise from the, again, that chemical ingredient addiction.
Jay (21m 47s):
So it really does ultimately help in all phases. But again, it's education. We really have to teach people how to do these, right? Because most people have no idea,
Brian (21m 57s):
Right? 'cause what I've noticed is, like we talked about earlier, is like, I mean, if you're not strength training and you're, do you know if you're not changing your lifestyle and strength training and you're just get on these, like you said, at a high dose, you lose fat, but you're also losing a lot of muscle. You
Jay (22m 12s):
Lose muscle more than you lose fat. Yeah, that's absolutely correct. And so I actually have, it's not in the book, it's kind of a social media landing page I built, but it's called the 10 Commandments of GLP use and the four that are really primary. 'cause the other six are really like for biohackers to optimize. But the four that must be met, and this is in the book, is number one obviously dosing, right? We must microdose number two is eating enough protein. So again, in that 95% of people who do it wrong, dude, they stop eating. I mean, so, but here's the conundrum and I wanna explain this. Like if you are fat or overweight or need to lose 25 pounds plus and you start with A GLP and you don't have this education, which again is 95% of people, right?
Jay (22m 56s):
When you take it, you start dropping weight because you're not eating as much, right? So if you're one of those people and you don't understand metabolism and you don't understand nutrition, which is again the general population, you think the weight loss in the first week to 10 days to 12 days or whatever is great, you know, my belt is going down, I'm losing weight. But obviously they're not eating enough protein, they're not strength training, as you said. And by the way, that's number three, right? So number one, microdose, number two, eat enough protein. Number three, strength train. I kind of put 3, 3, 3 1 and three B is, is strength train in cardiovascular. And then number four, and you can even make number four, number one is are you hormonally balanced or hormonally optimized?
Jay (23m 38s):
Because as you said, these are very powerful drug interventions. And if you're taking too high of a dose and you're not doing the other three things, you're gonna have muscle loss. And as soon as you have muscle loss, as you know, you're in metabolic hell, right? Because now you have thyroid dysfunction, people's hair falls out again, they have muscle loss, they lose weight, their metabolism slows down. It's a really, really bad thing to play. So as long as you educated on doing this, right, and you do those four things, it's almost impossible to have severe side effects or to have anything go wrong that's not actually, you know, call it positively impacting your life, which again, positively impacting your life is becoming insulin, you know, sensitive, dropping body fat, having more energy.
Jay (24m 22s):
'cause again, when you change the brainwave patterning, you automatically become more positive, you automatically become more uplifted, you automatically have more energy to actually exercise and do the things that we're talking about. So like I said, there's like six other things that we could go into living insulin controlled, getting sleep, mitigating, EMF, et cetera. But I don't think those are the biggest needle movers as compared to the first four.
Brian (24m 44s):
Yeah, no, this makes sense. What about other peptides, like for first time users? You know, I think, I'm just use myself as an example. Sure. I'm 45, I, I don't, I'm, you know, in in good shape. Yep. Been in good shape for a while, but you know, Now I, what I find is that, as you know, you might see this as you get a little bit older. It's like you have these little tweaks, these little injuries that can come about from when, how, you know, how you used to maybe lift back in the day. Yep. So it's a little, you just, you just sort of have to find what works for you in the weight room. And what would you say for someone that's, that's just trying to tweak a little bit, maybe not lose weight, but just maybe help build or maintain strength and, and in energy levels and things like that.
Jay (25m 28s):
Yeah, so it's a great question. So I just turned 55 on February 24th, so I understand all the wear and tear and the injuries. And again, you know, for the, for the audience, for your audience, I've been using therapeutic peptides since 2023, excuse me. 2 0 0 3. Yeah. Two, I wrote my book in 2023. But, so it's been close to, you know, 26, 23 to 24 years that I've been using therapeutic peptides. And I've been using therapeutic testosterone for 26 years, since 1999. Really actually 27 now. It'll actually be 27 technically in December. But to your question, there's a lot of amazing peptides in the marketplace right now. There's like 57 that are commercially available between research or direct to consumer companies and obviously compound pharmacies very, very soon for the public's knowledge, they're about to roll back all the peptides that were classified as type two in September of 2023, which it's not really important what it means.
Jay (26m 24s):
It's really kind of silly. But they're about to make them class one, and once they're class one, it means that anybody can prescribe them who's a medical practitioner who has a license to prescribe drugs. So it's gonna create a gigantic, like I was telling you off air, a gold rush, you know, into this space because of those 57 commercially available peptides. We've got stuff for healing, you know, know body protective compound 1 57, which you're familiar with, which is known as BPC 1 57, TB 500. Those are two amazing peptides that people can take in a microdose year round, you know, a couple times a week, couple times a month to avoid the injuries in the wear and tear, as you just said, you know, to heal faster. You know, they call that the Wolverine blend because it accelerates healing it, you know, anywhere from six to seven to even 10 times the level of just normal, you know, RA rice, you know, with the rice method of like rest, you know, elevation, ice compression.
Jay (27m 15s):
So you've got just amazing peptides from a healing standpoint. There's many other, I don't have to mention them. There's also stuff that builds muscle and, and, and, and burns fat. You've got like growth hormone agonist peptides like a TESS and like an IPAM and like a CJC, you've got cognitive, you know, enhancing or restoring peptides like cerebral lyin, DXA LAN P 21, there's others. And then of course you've got immunity peptides, amazing immunity peptides like thymosin alpha one, LL 37 VIP, which is Vaal intestine peptide. I mean, all of these peptides, if you understand how to use them. And again, I've written a book that's available on Amazon, if you go to my website, you can get the PDF for free.
Jay (27m 59s):
I'll say that at the end of the show. But it, you know, breaks down all these peptides and teaches you how to dose them, you know how to use them relative to your age, relative to your condition. I think the one thing to understand is about peptide usage that people get confused about is, and maybe it's two things on the same level, is that you don't wanna stack a bunch of peptides at one time that do different things. You know, people see peptides and then they get the shiny object syndrome and they're like, oh, I want that, I want that, I want that. I wanna do all these together. And I always tell people that's a mistake because number one, we wanna attack the biggest issue that you have for most Americans and really western people or first world people that are watching this podcast.
Jay (28m 41s):
It's fat loss, right? It's insulin resistance, it's too much inflammation, which is all those things. Again, insulin resistance and, and, and too much body fat. So we're probably gonna use like a GH agonist peptide and we're probably gonna use a GLP peptide and we're gonna use these things again in the context of health and longevity. So in micro dosages, you know, we're gonna use them a couple times a week to, depending on how much body fat you have to lose, and maybe three times a week. And we're gonna cycle these, right? We're gonna use these for six to eight to 10 weeks, and then we're gonna go off and then we're gonna assess our experience, assess our results, and then we're gonna decide what's next, right? So people will come to me when I say that and they'll be like, yeah, but dude, I sprained my ankle, right?
Jay (29m 21s):
Why I was attempting to lose body fat? And I'm like, okay, that's cool. So you need BPC and TB 500, right? So you can take those while you're taking the fat loss peptides, but you don't wanna jam 'em all together. And that's one of the mistakes that a lot of people make. And you know, I see this on social media all the time. You know, people are talking about putting six peptides in one syringe. And that is an absolute mistake because you cannot look at peptides and putting them all together like that because you have what is called cross chain linking, or cross chain reactions. And sometimes specific types of peptides that work on different biological systems in the body will cross each or cancel each other out and make one of the peptides inert.
Jay (30m 1s):
So it's very simple. Like I have this PDF that I give away, which, you know, at the end of the show, I give people a link to it. It's called the peptide cheat sheet. And it literally recommends what peptides can be used in, you know, together. You know, people call it stacking that you know, you could technically put in the same vial or blend them together and which ones you can't. And then it also has like recommended dosing for both men and women's. Most peptides are dosed accurately or dosed the same in men and women. The only difference is, is in like weight and size sometimes, like obviously a bigger person can handle a little bit more of a dosage. But I think the other thing to understand is too, is that when you're, when you're using peptides, you have to understand how to reconstitute them, especially if you're getting research peptides, which a lot of people are doing today, because like I said, the compounded version are so expensive.
Jay (30m 49s):
So you really have to understand like calculation. When
Brian (30m 52s):
You say, I'm sorry Jay, when you say research peptides? Yes. What do you mean by that? So
Jay (30m 58s):
Basically research peptides is what is known as research use only. And these are basically really what the legal system looks at is direct to consumer version. So you have manufacturers like my company, bio Longevity labs, that will sell them direct to you without a prescription, but when you get them without a prescription, you know, you obviously have to assess you're an adult and you have to, you know, assess that you're doing this to research on yourself, et cetera. But when you do that, you also have to understand dosing. You have to understand how to reconstitute a vial, how to put bacterial aesthetic water in a vial of actual pure, you know, lyophilized powdered peptide. But if you get it from a doctor, which you can, the doctor will actually send it to you already oph, excuse me, already reconstituted.
Jay (31m 41s):
And sometimes they'll even send you syringes with the water already mixed in them and you just inject, right? So the difference between research and compounded versions or that the compounded versions are much more expensive, but they're more done for you, whereas the research are more economically viable for most people. But you have to understand like how to do it, right? You have to understand how to dose and how to reconstitute. So there's a mix, there's a peptide out there from a style standpoint for pretty much anyone. But you really have to look at it from a standpoint of like, okay, do I want to pay the inflated markup of the compounded doctor prescribed model versus just doing it myself? Does that make sense?
Brian (32m 18s):
Yes. Got it. Yeah. And the, the ones on your site are all researched ones, right? Obviously you have to correct. And, and are all peptides as far as are, do you, is it a shot for every, for all of 'em, or
Jay (32m 32s):
No? So that's a great question. So there's many. So there's really lots of delivery systems. The most effective from a delivery system standpoint is always gonna be injection. And that's for two reasons. Number one, it crosses the blood-brain barrier the fastest. And then it also gets into what is called portal circulation the fastest. And so you're always gonna get the highest impact from injections, but there are oral versions. There's also intranasal, there's transdermal solutions you can put on your skin, on your face. A lot of women obviously use like copper peptide gh, HKCU for anti-aging purposes. 'cause it's a very powerful angiogenic peptide that enhances red blood cell formation and also improves collagen and fine, removes fine lines and wrinkles and improves elasticity, et cetera.
Jay (33m 15s):
But those, those are your four primary pathways for delivery system pathways. But right now, Brian, there's a lot of technology being exper, you know, basically created where they're working on like what are called micron patches. And micron patches are gonna literally be like Velcro patches where you just put it on your arm and it'll have a very, very, very thin tiny, call it hypodermic needle. Right now the, the technology is up to like 20. But once they have like 40 to 60, you'll be able to take any peptide. Because again, And you know, I don't wanna get too technical with the chemistry, but the difference between an oral peptide and injectable peptide in efficacy is that all peptides are, you know, again, call 'em biomolecules or chains of amino acids, the longer the chain, the more likely it has to be injected.
Jay (34m 3s):
Whereas the shorter the chain of amino acids, the more often you can take it orally because it's just more viable orally. And again, it's just the size of the actual chain of amino acids. The shorter the size, the more often you can take it orally. The longer, the more it needs to be injected. But again, that technology will eventually, I would think it's within a year to two, maybe even shorter. 'cause technology's improving so fast with AI where you'll be able to take any peptide with that. And I've used them, you know, these guys come to me all the time and they talk about their tech and they wanna experience it with me and say, Hey, we want to, you know, partner with you in this way. And so I've used a lot of these and honestly, you can't feel it at all. There's zero pain. And clearly in the marketplace today, there's a lot of people that have needle phobia.
Jay (34m 43s):
You know, they're afraid of injections. I mean, a 30 to 31 gauge insulin needle or even a pen, you can't feel. But until somebody injects themselves a couple of times, there's always gonna be that phobia of injecting. Sure. But it's really, really simple to get over it. It's like I tell people it's like brushing your teeth after you do it once or twice, you know, it's just like old hat. You can just do it every day and you don't have a problem with it. But I really am excited because some of these newer technologies will eliminate that fear of injections. And so you're gonna have much more wider adoption of people using peptides.
Brian (35m 13s):
Hmm. What's one thing you've changed your mind on in this, in this sort of area of health? Yeah,
Jay (35m 20s):
Man, that's a great question. Nobody's ever ever asked me. That's an awesome question. Thank you. One thing that I've changed my mind on is just the idea that peptides would gain mainstream and widespread exposure like this. Like my attorney who literally just texted me on my iChat, as you and I are talking, so you talk about the universe, how crazy is that? He said to me last week on Thursday, because you know, I think it was, it was actually last Tuesday, it was a week ago from today when everything started going on the social media about RFKs little snippet on Joe Rogan podcast talking about how it was illegal, what the FDA did when they rolled back the peptides in 2023 and that he's actually, they're, they're, they're, they're dead panning that now, and they're moving all those class two peptides back to class one.
Jay (36m 6s):
He texted me, 'cause I sent him that clip, it was starting to go mainstream and go viral. And he called me later that day and he said, dude, because he's like 64 years old, he said, in my whole life, I never thought that we would ever live to see this day. So that would be my answer, is that I never thought this either. I mean, look man, when I was using peptides in 20 2003 all the way till like 2012, I was always like, you know, in the shadows, I, I didn't wanna tell people I was doing this, it was just this yeah. Weird gray area where it was like, technically not illegal, but you didn't tell your mom or dad or your brothers or sisters about it. You know, you were doing it in the shadows and fast forward, here we are today, and it's like everybody's doing it. So that's what I really kind of think is that, you know, I never thought of this.
Jay (36m 48s):
Look, I'll be honest, like if I would've built my company Bio Longevity Labs in 2013, like Peptide Sciences did in 2009 or 10, bro, I'd be a gazillionaire. I mean, I, I would definitely be living on an island somewhere, but I didn't have the courage, you know, to really do it. Because like I said, I saw it as just like this really gray, you know, unregulated, unlicensed, unregistered area. But it, in truth, I just didn't understand the law as well as I did. And obviously those guys at Peptide Sciences did, and they really took advantage of that. And, and obviously now it's just a full blown mania in the world.
Brian (37m 25s):
And you know, I know supplements aren't necessarily that highly regulated. What's the regulation as far as peptides?
Jay (37m 33s):
Yeah, so it's a good question. It's unfortunately right now in the research space, there are, there are definitely bad actors. And what I mean by that is, I wanna explain that, is that there are a lot of companies that are literally making stuff when people say in their basement or their kitchen, what they're really doing is they're buying the peptides from China. Because right now in the world, there are two places that actually have what are known as API and API literally stands for pharmaceutical ingredients, you know, applied pharmaceutical ingredients. And because it's so cheap to manufacture in China and so cheap to manufacture in India, that's where all these giant call it warehouse manufacturers are with Lyophilizers and all the ingredients and the chemical equipment needed to process peptides and synthesize peptides.
Jay (38m 19s):
And again, it's just too such an expensive process has never been done in the United States. So what these people do, again, call 'em the bad actors, let's just call 'em bad actors for this conversation. They import these peptides from China. They have no sterility processing control, there's no testing. They're just relying on the, you know, the promise of the manufacturer in China that they're sending 'em good stuff. Now, thankfully, for most people in the global public, most of the stuff that does come outta China is not tainted. It's not bad, it's not chemically inert. But the other problem that we have, part of it is that a lot of it is right, not bad, but just fake. It's just underdosed, counterfeit bunk, whatever. And so you've got a lot of people in this space right now selling peptides that you'll see on Instagram or TikTok or Google or wherever, you know, I always say warehouse peptides or something like that.
Jay (39m 8s):
You know, you go on Facebook or social media and they target you and they say, Hey, buy peptides from us. A lot of those people are, are fake. They're, they're absolutely selling low grade counterfeit bunk peptides. In fact, I was just on a peptide podcast in California that hasn't even appeared yet with doc, not doctor, but Trevor Kruger and another name, and Trevor's one of the biggest manufacturers of peptides in the world. He, he manufactures for research and he also manufactures for compounders. He owns a ton of compound pharmacies. And he said that in their tests of buying peptides from the general marketplace and then running them through their testing companies and, and, and, and really the independent verification, he thinks that up to 70% of research peptides right now are fake.
Jay (39m 52s):
And when I say fake, it doesn't mean that they're completely, you know, inert, but a lot of them are underdosed, they're poor quality. Again, they're coming outta China, for example, you could buy a hundred vials of peptides from China, from these warehouse manufacturer sellers. And they may sell, send you 80, that are 99% pure. And then the other 20 are fake. So if you are that guy or gal buying these peptides and then taking the labels off, a lot of 'em are, they're sending 'em unlabeled. And so people are literally making labels up on their computers in their house and putting them on these files and selling 'em to people. You know, after you've done that for six months, 30%, 25%, 35% of the peptides you're selling are fake.
Jay (40m 33s):
So it's just become this like scandalous, you know, industry where there isn't right now universal quality control. And when I say quality control, this is what I mean, 'cause this is very important for your audience. There has to be what is called chain of custody. And chain of custody shows where the peptide was manufactured. It's in listed online, it's, look, you can look it up online, it has a batch number, a lot number. And then it has where called independent third party certificates of authenticity and verification that proves that if you need to look this peptide up, where it was manufactured, where it was produced, that it shows that it's, it's 99% or 98.9% or whatever it is, pure of impurities, endotoxins, you know, LPS, which are called lipopolysaccharides.
Jay (41m 23s):
You know, Andrew Huberman talks about that all the time. But the good guys have that, like my company, we spent a fortune in testing an independent third party verification so that people know that what we sell is legit, right? We don't sell fake products, unfortunately, there are not enough people doing that. And right now there is no call it, you know, third party vetting other than people just buying online and trusting the source. So it's like, I always tell people, just as in the supplement industry, which as you know, is very unregulated, I mean I've been in the supplement industry before. I was in the peptide space for a long time and I can tell ya that people spike protein powders, they do all sorts of crap in that industry. Until there is an independent vetting or verification third party company that's testing all of them.
Jay (42m 8s):
You are definitely gonna have to be buyer beware just as you've always had to be buyer beware in the supplement industry, right? I always tell people when they ask me to buy protein powders, I'm like, has the company been around 20 years? You know, have they been around 10 or 15 years? Do they have a really good online, you know, viable reputation? If they don't, why would you buy from them? You know? 'cause you're basically just going on a guess. There's no way for them to verify. So it's the same thing in the supplement industry that's in the peptide industry. Just make sure that where you're buying your peptides from are independently verified.
Brian (42m 37s):
Got it. And like what, what two, or, I know you might have mentioned it sort of quick, but maybe just to rehash what like two or three peptides would you consider like foundational for a man like in his forties and fifties that maybe he's trying to just sort of rebuild metabolism?
Jay (42m 51s):
Yeah, so that's a great question. So number one, and I say this in the book and I've always said this, and obviously I'm an OG hormone guy. Hmm. If you are not hormonally balanced or optimized in your, in your forties, and by the way, most men listening to this show, and most men anywhere, at least in the first world are not, you're not gonna get the same results as somebody on peptides who is right. So the first step is always, am I hormonally deficient or am I getting my labs tested? Do I know if I'm functioning with a hormone deficiency? Because if I am, I'm not gonna get the same results as someone who is hormonally balanced or working to get hormonally balanced. So first step is to get your labs done.
Jay (43m 31s):
You know, measure your total free and your sensitive estradiol, which is again your estrogen levels. Understand if you're working with a hormone deficiency and if you are, you know, change your lifestyle dramatically to get your hormones optimized or you know, use the biggest tool in the tool belt, which is therapeutic testosterone. But, but always again, buyer beware. Make sure you're working with a doctor who can hormonally optimize you. The good news is in the United States now there are plenty, but there's still a lot of also bad actors. So you gotta make sure you're working with people that understand and do that, right? And then once you're hormonally balanced, optimized or working to be that way, then you're looking at really primarily probably again, identifying what your biggest issue is. For most men it's fat loss, insulin resistance, inflammation, A-A-G-L-P, either two or three.
Jay (44m 17s):
And I'll just say this for this show 'cause you've been asking great questions. GLP two, which is obviously the FDA approved version of tirzepatide, which again is Zep or Manjaro is a great choice. It's just more expensive than GLP three, which is Reddit Tru Tide. The problem is now is that IDE isn't really found by any research chemical manufacturers like it was the previous two years because Lilly is coming after people because they're about to approve it and they're saying you don't have a right to sell it as a research chemical. 'cause we're about to make it an FDA approved drug. So it's harder now for people to use IDE anywhere because it's not available now. Eventually, I think I'd say, you know, right now is today, today's March 10th, I don't know when this will run, but I think this product is gonna be meaning Redit tru Tide, which is GLP three, I think it's gonna be FDA approved by the late summer.
Jay (45m 7s):
And if it's not, it'll be FDA approved by early, you know, just call it early fall, third quarter. So that's what, that would be my number one recommendation if you could get it. But if you can't, GLP two is a mi, you know, a microdose of that again, to increase metabolism, mildly suppress appetite, change, change, brainwave patterning. And then from there, depending on how much fat loss you have or need and also how much muscle you want to gain, you can look at GOP, excuse me, GH agonist peptides like Tessa ipa, cjc. My favorite is Tessa, if you have a lot of belly fat as a man, Tessa Marin is the best peptide to use because it's actually an FDA approved peptide to cut through visceral fat in the belly.
Jay (45m 47s):
And so you can buy that in the research space or also in the compound space. And then I would also just add, depending on, you know, like you were saying, if you have wear and tear, you're a little older, you want to repair injuries, my company sells a blend called Reno, and Reno is BPC TB 500 and a Russian bio regulator, which is called Carla, which actually helps to rebuild cartilage and, and, and resensitize cartilage tissue. So that's like your ultimate healing blend. So something like that would also be really good for wear and tear. And of course if you're critically injured, you acutely injured and sprain your ankle, blow your knee out, blow your elbow out, blow your shoulder out, then that's gonna be really good injected locally at the point of origin to massively heal.
Jay (46m 29s):
And then I would be remiss if I didn't also say there's a lot of mitochondrial peptides. You know, right now in longevity, mitochondrial optimization is the rage. Like everybody's talking about mitochondrial optimization. And the three or four peptides that I recommend for mitochondrial optimization are, and the good news is there's oral ones. There's a product called SLU PPP dash three thirty two, which we affectionately call sloop. And Sloop is an incredible oral peptide that maximally increases a TP synthesis or a TP production. So when you're taking it, you're stronger, you're leaner, you're more energetic, you have more room, you have more force production when you're lifting, you have more firepower when you're doing cardio.
Jay (47m 13s):
So it's like an, it really is like a cheat code slash easy button to improve metabolism and metabolic health, that's again called SLU PPP dash 3 32. We sell that at Bio Longevity Labs is a product called Shred Max. And then the other ones would be, which would be injectable, would be, there's three of them and, and you probably have heard of them, one of them is MOT C, the other one is NAD plus. And then the other one, there's the, the other one is called, actually there's two more that are really awesome. Five amino, one mq, which is injectable. There's also an oral version. It's not as strong orally as it is injectable. And then the other one, which is probably the one that is probably the most powerful, but now is also the hardest to get because the FDA just approved it as a drug called a LAMA ide.
Jay (47m 56s):
It's called SS 31. It used to be called SS 31. And SS 31 is like an amplification peptide. When you take it, everything else that you're taking is improved. So if you're taking therapeutic testosterone, you know, if you're taking like a blood glucose regulating product like a Metformin or dihydro, berran, all of these things, you can lower your dose because SS 31 is amplifying the cellular signals and cascades to make the, you know, usage or efficacy of the stuff you're taking actually more efficient at the cellular level. So it's a really profound peptide. But those would be the ones that I would really consider. You know, the other stuff that we talked about earlier would be be more specialist. You know, if you got sick, if you really wanted to regulate your, improve your immune function, you could use TA one.
Jay (48m 39s):
If you wanted to improve brain speed or really help your brain pathways, you could use cerebral or dxa or even LAN or Cmax. But those are all that I, you know, you just kind of keep 'em on the side for if you need to do something special, the other ones would be more foundational.
Brian (48m 54s):
Got it. And what about, I thought I saw one product that you have for sleep. Is there, is there any peptide to help for sleep?
Jay (49m 2s):
There is. There's a peptide called DSIP, which is Delta Sleep Inducing Peptide. I don't use it personally. I sleep pretty good, you know, I do a lot of stuff to mitigate things in my life. My room is blocked out and sure I sleep on like a Faraday type bed and stuff like that so that I can block EMF. But you know, for most people. What type
Brian (49m 23s):
Of bed?
Jay (49m 23s):
Sleep. I sleep on a bed. It's called, what is it? What is it called? But it has like a built-in Faraday cage around it or whatever. So when I get into it, there's no EMF.
Brian (49m 33s):
You're like in a shell. Yeah,
Jay (49m 35s):
Exactly. I mean, it's like a cage. It goes around. And so me and my wife can sleep in it and we can, you know, have no EMF hitting us. But DSIP is a good peptide for some people. I just think that a lot of sleep issues are eating too late. Not, you know, EMF mitigating or EMF proofing your, your, your room that you sleep in. You know, if you've got like wifi, I mean dude, a lot of people plug their fucking phone in next to their head when they go to bed at night and you can't do that, right? So there's a lot of things to do to EMF mitigate or to mitigate EMF in your house or where you sleep, your apartment, whatever. But for, obviously I'm super advanced in all that stuff and so I really take my sleep very seriously. But DSIP is a good sleep inducing peptide for a lot of people.
Jay (50m 17s):
You know, melatonin, high dose melatonin. There's also a really awesome bio regulator that we sell called Pineal on. It's actually we just call it bio pineal and that also helps, you know, deep inducing sleep or getting into re, what do you call it, polyphasic sleep. So there's lots of stuff you can use, but the peptide, the one primary peptide that helps with sleep is D-D-S-I-P.
Brian (50m 40s):
Got it. Well this was great. I mean, I'm sure for some people this sounds like another language, you know, some people listening might, might have more knowledge, but yeah, I know that you know it getting your book or I know you said there's, you have a PDF that you give away as well, correct?
Jay Campbell (50m 58s):
Yeah. So if, for anybody who listened to this podcast today, I have a domain that I give away all my books. The, the, the newest book, which is again called Metabolic Awakening with GLP one Peptides is not available yet for free, But it will be probably within the next 30 days. You know, after the first six weeks the book is on the market, I always give away all my content for free. So you can go to Jay Campbell dot com slash free dash info and you can get all the books that I've written previously. It's got all my testosterone books, all my intermittent fasting or maximizing intermittent fasting fat loss books. My peptide book from 2023. I have an awesome fat loss book from 2023 called 30 Days to Shreds and it kind of outlines how to lose the most amount of fat in the shortest amount of time, in the most healthy and efficient way possible. So that's a really awesome book that's there. And then this book is without a doubt, my magnum opus, it's not free yet, but obviously if you follow me you can get it for free. I give away the PDF to my email listeners all the time, my email list. So if you go to join dot Jay Campbell dot com at least once a week, what there, there'll be a link on there on how you can get the PDF for of the book for free. But look, I recommend people go to the book, go to Amazon if they are using LPs and actually get a hardback or paperback copy of the book because there's so much intel that you're gonna refer back to, you know, over the course of your life, especially when you really wanna understand what not to do. And so obviously the book is, you know, it's really on sale right now from Amazon because it's selling so fast. I think you can get the paper back again. It's a 700 page book for like 24 bucks. So it's definitely worth getting the paper back and highlighting the sections that you're gonna go back to 'cause there's so much information in it. Got it. And I'll put links in the show notes so people can, you know, find you also your, your company Bio Longevity Labs as well. Yeah, Yeah. For, so if people, and Brian, I'm happy to give you a coupon code if you want to use as an affiliate 'cause we'd love to have you for now there's a lot of people in my affiliate marketing group, but if you use JAYC or maybe we'll use Brian g, you know, if Brian ends up having one, you'll get be able to get 15% off any of your purchases. And you know, very truthfully, we run a lot of sales at my longevity. So there's always times every single month where you can get your products up to 45% off. And look, we're not gouging people. You know, we wanna make, as we like to say, we are democratizing peptides. So we're making them as affordable as possible because we want as many people around the world to become exposed to them as possible.
Brian (53m 30s):
Love it. Yeah, and I think just from watching this, they'll get a good idea of you know, places where to start, you know? Sure. So,
Jay (53m 37s):
Yeah, no doubt man.
Brian (53m 38s):
Well Jay, I appreciate you coming on. This was great. We haven't had too many peptide guests on, so thanks, thanks so much for dropping all the knowledge today.
Jay (53m 47s):
Yeah, for sure man. And if you want me to come back, you know, if you get a lot of, you know, feedback and people are like, I have no idea what that guy just said, but I'm interested, you know, just have me come back and we can even just go down like fat loss, you know? Right. Cognition, enhancing, G Ps, et cetera. We can even get into like the dosing practices and stuff like that. I'm happy to do that. But if they, if they go to join dot Jay Campbell dot com, one of the things that they will get is the peptide cheat sheet sent to them automatically. So, you know, that'll really, really help. 'cause that's like one of the best tools in the whole world on like really understanding what a peptide does, how to dose it, where to get it, et cetera. Hmm.
Brian (54m 20s):
Love that. All right Jay, well have a great rest of the day and I appreciate you coming on.
Jay (54m 25s):
Thank you Brian. You too, man. Have a great day. Thank you.
Brian (54m 28s):
Thanks for listening to the show. I know there's thousands of podcasts out there and you chose to listen to mine. I will put a link in the show notes if you want to connect with my guest. And if you are looking for one-on-one consulting with me, I will put a free 15 minute link so you can set up a call to see if you're fit for my six month health breakthrough program. So thanks again, feel free to rate and subscribe. I would love that to help support the podcast. And till next time, have a great rest of the day and I'll see you on my next podcast. Thanks so much.
