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episode #245

New Paper: Omega-6 vegetable oils as a driver of coronary heart disease

April 24, 2023 in Podcast


This week I discuss a recent paper titled:Omega-6 vegetable oils as a driver of coronary heart disease: the oxidized linoleic acid hypothesis. This paper goes through details regarding the evidence implicating omega-6-rich vegetable oils as a causative factor in atherosclerosis and coronary heart disease.

The intake of omega-6 vegetable oils, particularly soybean oil, began to increase in the USA starting in the early 1900s at a time when the consumption of butter and lard was on the decline. This caused a more than two-fold increase in the intake of linoleic acid, the main omega-6 polyunsaturated fat found in vegetable oils.

In summary, evidence shows that the omega-6 polyunsaturated fat linoleic acid promotes oxidative stress, oxidized LDL, chronic low-grade inflammation and atherosclerosis, and is likely a major dietary culprit for causing coronary heart disease especially when consumed in the form of industrial seed oils commonly referred to as ‘vegetable oils’.

The best way to avoid consumption of these vegetable oils is to cook for yourself with ghee, butter, tallow, coconut oil and/or extra virgin olive oil. Also, be sure to read any labels because these oils are everywhere!

Have a great day!

Brian (1s):

Hello and welcome to the Get Lean and Eat Clean podcast. My name is Brian grn. I'm a certified health coach, trainer and author, and this podcast is for middle-aged men and women looking to optimize their health and get their bodies back to what it once was 10 to 15 years ago. I will give you simple, actionable items to get long-term sustainable results. Thanks for listening and enjoy the show. All right, welcome to the Get Lean e Clean podcast. My name is Brian Grn. I hope you had a great weekend and hope you listen to my recent interview with Georgie Dinko.

Brian (42s):

Georgie is a independent health researcher, like pretty much a walking encyc encyclopedia, and he comes from sort of the bio energetic viewpoint. And so we touched on sort of his thoughts around insulin resistance re regarding stress and fasting and fat versus glucose oxidation. Also advantages of taking niacinamide vitamin E and aspirin. And we also touched on certain health markers that you should look for. One of them was cortisol to D H E A, which was really interesting. He's touched on that on a few other podcasts. So he's a fast talker. I definitely recommend you listen to it maybe more than once because he, he's got a lot to share and it goes really fast.

Brian (1m 25s):

So definitely check that one out if you haven't already. That's episode 2 44. And now today's micro podcast, we're gonna touch on a paper that is, was written by James D and James O'Keefe, and it's Omega six vegetables as a driver of coronary heart disease, the oxidized Eliminate acid Hypothesis. And I thought this was a relevant topic to talk about because Georgie talks a lot about pfas and the intake of omega six vegetable oils and how this has just been on the rise. And it touches on this in the paper. And I'll sort of read some of the quotes and you know, the, sort of the highlights. So you can get, if you wanna go deep dive deeper, I'll leave a link in the show notes.

Brian (2m 8s):

So definitely check that out. But this intake of omega six vegetables, particularly soybean oil, and this began got an, as you know, the increase in the United States, it was a cheap way to sort of fortify foods and make sure that they're, that they essentially cheap way of cooking, I would say, as opposed to using butter or lard. So it was like sort of an increase of this omega six s, these vegetables starting in the early 19 hundreds. And so there was a twofold increase in the intake of linoleic acid, the main Omega six unsaturated fat that's found in vegetable oils.

Brian (2m 47s):

And so Georgie talks a lot about this, so I thought it would be relevant to talk about this now. And it makes up about eight to 10% of the total energy intake of the western world. So Omega six fat linoleic acid should not be confused with c l a conjugated linoleic acid, which is in pastured animal foods. And so you see this sort of rise in these omega six fats, linoleic acid and this decline in conjugated linoleic acid. And so, so the theory here is that essentially there's this two and a half fold increase in lineate acid increasing from 9.1% to 21.5% from 1959 to 2 0 8.

Brian (3m 33s):

And this was, they measured by the concentrated concentration in this subcutaneous adipose tissue. So it's a, it's crazy. The, the, the concentration of linoleic acid in adipose tissue essentially is a reliable marker of intake because the half-life of linoleic acid is approximately two years in your adipose tissue. So the, the study from these authors noted that this increase in adipose tissue, lin o lake paralleled the increase in prevalence of diabetes, obesity, and asthma. So now this, we're starting to hear more and more in the health space, and rightfully so, because they're everywhere and you can't taste them, you can't tell they're in foods, but if you start looking at labels and you're going out to restaurants all the time, this is what they're using.

Brian (4m 25s):

They're using these soybean oils to cook in soybean oil, sunflower oil, you name it. There's, I could probably do a wrap song. There's like 12 of them wrap seed oil. All of these vegetable oils and the summary of this paper pretty much prove the fact that it's a causative factor in, as in, in atherosclerosis and coronary heart disease sort of implicated omega six rich vegetables as sort of the causative factor of those. And it's been on the rise as diabetes, obesity and asthma's been on the rise. And essentially linoleic acid cannot be synthesized in the body.

Brian (5m 6s):

And it suggests that patients who have heart disease consume more of these omega six linoleic acid than those without heart disease. So it really goes into a little bit more of the science. And essentially another quote that I got from it was the fact that, you know, this linoleic acid gets into your adipose tissue and essentially is this, there's this positive association with coronary art artery disease. And essentially the opposite is true, but these long chain omega three s, which is E P A D H A, which you hear a lot about, and the levels in these platelets are inversely related to coronary artery disease.

Brian (5m 47s):

So there's a positive association with this linoleic acid with coronary artery disease. And there's a sort of an inverse relationship if you have more omega three s. And so this ratio has sort of gotten out of whack since, gosh, the early 19 hundreds. And as I said before, it's gone up two and a half fold from 9.1% to 21.5% from 1959, just 2008. So I can't imagine that's 2008. I can't imagine what it is now. So I think it's just something to, to keep in mind. One other sort of quote that I, that I found within the paper that I thought was interesting, it said mice fed, mice fed fish high omega-3 S as compared with corn oil high omega six have a significant reduction in their a thorough sclerotic plaque formation, possibly due to an increase in an an antioxidant enzyme activity.

Brian (6m 43s):

So this was just one done on talking about mice fed with the fish oils and high in omega three s as compared to corn oil. And sort of the, how there was the, the, the mice fed with the omega three s, there was a reduction in atherosclerotic plaque compared to the the corn oil. So I think there was plenty of evidence in this, in this. And and to summarize, essentially the evidence show that the Omega six polyunsaturated fat linoleic acid promotes oxidative stress, oxidized ldl, chronic low grade inflammation and atherosclerosis. So it's likely a major dietary culprit for causing coronary heart disease, especially when consumed in the form of industrial seed oils commonly referred to as vegetable oils.

Brian (7m 33s):

So I think you got the point. If you wanna read a little bit more into the paper, I will leave a link in the show notes. And I think a good place to start would be to try to just cook at home for yourself and not go out to eat because they are using these vegetable oils at every restaurant that you go to. You can always ask them not to cook in them and ask to be them to cook in some type of saturated fat, maybe butter or gee if they have that. So just make sure when you're cooking at home, you're controlling it. So cooking, I like to use GH butter. You can use Tao, you can even use coconut oil, even avocado oil, make sure it's pure avocado oil and even extroversion olive oil.

Brian (8m 14s):

So u use those oils as opposed to these seed oils and I think you'll be a lot better off. And this paper definitely summarizes that very well. So hope this helps. Hope you enjoy the micro podcast. If you do love a love a review and five star review and any questions or comments, right 'em below or email me, brian brian grn.com. And I hope you have a great rest of the week and I'll talk to you on Friday with another great interview. Thanks so much. Thanks for listening to the Get Lean ean podcast. I understand there are millions of other podcasts out there and you've chosen to listen to mine and I appreciate that. Check out the show notes@briangrin.com for everything that was mentioned in this episode.

Brian (8m 59s):

Feel free to subscribe to the podcast and share it with a friend or family member that's looking to get their body back to what it once was. Thanks again and have a great day.

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